Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 11/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342022 | 0.80 | FPR1 (0.42) | MTNR1A | |
| SCHEMBL8358430 | 0.77 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL14823518 | 0.75 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL25048767 | 0.75 | PDE4A (0.50) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL21342012 | 0.74 | MTNR1A (0.49) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL20789976 | 0.73 | ALDH1A1 (0.50) | CYP3A4ALDH1A1CYP1A2MAPTCYP2C9 | |
| SCHEMBL17514730 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTKMT2AEGFR | |
| SCHEMBL10401509 | 0.73 | HTR2C (0.56) | PDE4B | |
| SCHEMBL1613815 | 0.72 | ALDH1A1 (0.55) | CYP3A4ALDH1A1CYP1A2CYP2C9KMT2A | |
| SCHEMBL22204489 | 0.72 | PDE4A (0.48) | DDB1CRBNPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062018-A1 | Novel phenyl-piperidines | Aktiebolaget Hässle (SE) | 1982-10-06 | — | — | EP | disclosed |