Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | FPR1 | P21462 | 5/20 | 0.44 |
| ▸ | FPR2 | P25090 | 4/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19559399 | 0.86 | MTNR1A (0.64) | MTNR1AFPR1FPR2PDE4APDE4B | |
| SCHEMBL18117787 | 0.86 | MTNR1A (0.64) | MTNR1AFPR1FPR2PDE4APDE4B | |
| SCHEMBL21342022 | 0.82 | FPR1 (0.42) | MTNR1AFPR1FPR2 | |
| SCHEMBL20010674 | 0.81 | CPS1 (0.40) | FPR1FPR2PDE4APDE4BPDE4C | |
| SCHEMBL19988384 | 0.78 | MTNR1A (0.49) | MTNR1AFPR1FPR2PDE4APDE4B | |
| SCHEMBL10736004 | 0.75 | MTNR1A (0.43) | MTNR1ADDB1CRBN | |
| SCHEMBL21341944 | 0.75 | HTR2A (0.55) | HTR2C | |
| SCHEMBL1529068 | 0.74 | HTR2C (0.58) | FPR1FPR2HTR2C | |
| SCHEMBL11295068 | 0.74 | DDB1 (0.43) | MTNR1ADDB1CRBNPDE4APDE4B | |
| SCHEMBL21342014 | 0.74 | FPR1 (0.53) | MTNR1AFPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |