Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979698 | 1.00 | TLR8 (0.46) | TLR8ALDH1A1POLBKMT2ACA1 | |
| SCHEMBL218249 | 1.00 | TLR8 (0.46) | TLR8ALDH1A1POLBKMT2ACA1 | |
| SCHEMBL29138650 | 1.00 | TLR8 (0.46) | TLR8ALDH1A1POLBKMT2ACA1 | |
| SCHEMBL9408468 | 1.00 | TLR8 (0.46) | TLR8ALDH1A1POLBKMT2ACA1 | |
| SCHEMBL216892 | 1.00 | TLR8 (0.46) | TLR8ALDH1A1POLBKMT2ACA1 | |
| Hydrochloric Acid SCHEMBL28508791 | 0.98 | TLR8 (0.47) | TLR8ALDH1A1POLBKMT2ACA1 | |
| SCHEMBL31037672 | 0.94 | AGTR1 (0.42) | TLR8ALDH1A1POLBKMT2ACA1 | |
| SCHEMBL31590567 | 0.93 | ALDH1A1 (0.47) | TLR8ALDH1A1POLBKMT2ACA1 | |
| SCHEMBL5282914 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 | |
| SCHEMBL2149023 | 0.88 | TLR8 (0.59) | TLR8ALDH1A1POLBKMT2AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108384496-A | A kind of black glue and preparation method thereof | 上海嘉好胶粘制品有限公司 | 2018-08-10 | — | — | CN | claimed |
| EP-3728487-B1 | METHOD OF REMOVING POLYMERIC MATERIAL COMPRISING HETEROATOMS FROM A SURFACE USING COMPOSITIONS INCLUDING A KETO-ESTER COMPOUND | FOURTH PRINCIPLE LLC (US) | 2025-07-02 | — | — | EP | disclosed |
| WO-2023091342-A1 | PRESERVATION SYSTEM FOR STABILIZING SPORE-FORMING MICROBIALS | PHIBRO ANIMAL HEALTH CORPORATION (US) | 2023-05-25 | — | — | WO | disclosed |
| US-20230151324-A1 | PRESERVATION SYSTEM FOR STABILIZING SPORE-FORMING MICROBIALS | PHIBRO ANIMAL HEALTH CORPORATION (US) | 2023-05-18 | — | — | US | disclosed |
| US-11370996-B2 | Compositions including keto-ester compounds and methods of using the same | FOURTH PRINCIPLE, LLC (US) | 2022-06-28 | — | — | US | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-20200377823-A1 | COMPOSITIONS INCLUDING KETO-ESTER COMPOUNDS AND METHODS OF USING THE SAME | TALK ABOUT IT SOLUTIONS | 2020-12-03 | — | — | US | disclosed |
| EP-3728487-A2 | COMPOSITIONS INCLUDING KETO-ESTER COMPOUNDS AND METHODS OF USING THE SAME | Fourth Principle, LLC. (US) | 2020-10-28 | — | — | EP | disclosed |
| CN-104981524-B | Organopolysiloxane compositions vulcanizable at ambient temperature into elastomers and novel organopolysiloxane polycondensation catalysts | 埃肯有机硅法国简易股份公司 | 2020-03-13 | — | — | CN | disclosed |
| US-9732071-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| CN-105073922-B | Article with antifouling properties, intended for aquatic uses and, in particular, for marine uses | 蓝星有机硅法国两合公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-105008473-B | Articles having antifouling properties for water applications and in particular marine applications | 蓝星有机硅法国两合公司 | 2017-04-19 | — | — | CN | disclosed |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2017-04-06 | — | — | US | disclosed |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | SENOMYX INC (US) | 2017-03-30 | — | — | US | disclosed |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
| CN-105073922-A | Article with antifouling properties, intended for aquatic uses and, in particular, for marine uses | BLUESTAR SILICONES FRANCE | 2015-11-18 | — | — | CN | disclosed |
| CN-105008473-A | Articles having antifouling properties for water applications and in particular marine applications | BLUESTAR SILICONES FRANCE | 2015-10-28 | — | — | CN | disclosed |
| CN-104981523-A | Organopolysiloxane composition suitable for vulcanisation into an elastomer at room temperature and new organopolysiloxane polycondensation catalysts | BLUESTAR SILICONES FRANCE | 2015-10-14 | — | — | CN | disclosed |
| CN-104981524-A | Organopolysiloxane composition suitable for vulcanisation into elastomer at room temperature and new organopolysiloxane polycondensation catalysts | BLUESTAR SILICONES FRANCE | 2015-10-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | TAS2R5, TAS1R1, TAS2R1 | TLR8 149/4885ALDH1A1 1490/4885POLB 3476/4885 |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | TRPA1, PDE6G, PDE6D | TLR8 416/4885ALDH1A1 1029/4885POLB 3252/4885 |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | TLR8 225/4885ALDH1A1 3880/4885POLB 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.