SCHEMBL216892

SCHEMBL216892

CCCCCCCCCc1nccn1CCO

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.46
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
KMT2A Q03164 1/20 0.45
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
AGTR1 P30556 1/20 0.43
AGTR2 P50052 1/20 0.43
KCNH2 Q12809 2/20 0.40
TLR7 Q9NYK1 3/20 0.38
ALPG P10696 1/20 0.36
PLAA Q9Y263 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979698 1.00 TLR8 (0.46) TLR8ALDH1A1POLBKMT2ACA1
SCHEMBL218249 1.00 TLR8 (0.46) TLR8ALDH1A1POLBKMT2ACA1
SCHEMBL18339282 1.00 TLR8 (0.46) TLR8ALDH1A1POLBKMT2ACA1
SCHEMBL29138650 1.00 TLR8 (0.46) TLR8ALDH1A1POLBKMT2ACA1
SCHEMBL9408468 1.00 TLR8 (0.46) TLR8ALDH1A1POLBKMT2ACA1
Hydrochloric Acid SCHEMBL28508791 0.98 TLR8 (0.47) TLR8ALDH1A1POLBKMT2ACA1
SCHEMBL31037672 0.94 AGTR1 (0.42) TLR8ALDH1A1POLBKMT2ACA1
SCHEMBL31590567 0.93 ALDH1A1 (0.47) TLR8ALDH1A1POLBKMT2ACA1
SCHEMBL5282914 0.88 TLR8 (0.59) TLR8ALDH1A1POLBKMT2AAGTR1
SCHEMBL2149023 0.88 TLR8 (0.59) TLR8ALDH1A1POLBKMT2AAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10570243-B2 Non-tin catalyst for curing alkoxysilyl-containing polymer MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-02-25 US claimed
EP-3494162-A1 NON-TIN CATALYST FOR CURING ALKOXYSILYL-CONTAINING POLYMER Momentive Performance Materials Inc. (US) 2019-06-12 EP claimed
WO-2018049375-A1 NON-TIN CATALYST FOR CURING ALKOXYSILYL-CONTAINING POLYMER MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-15 WO claimed
US-20180072837-A1 NON-TIN CATALYST FOR CURING ALKOXYSILYL-CONTAINING POLYMER MOMENTIVE PERFORMANCE MATERIALS INC. 2018-03-15 US claimed
WO-2026105516-A1 METHOD FOR FORMING MULTILAYER COATING FILM 日本ペイント・オートモーティブコーティングス株式会社 2026-05-21 WO disclosed
WO-2026105512-A1 CLEAR COATING COMPOSITION 日本ペイント・オートモーティブコーティングス株式会社 2026-05-21 WO disclosed
US-20250236755-A1 COATING COMPOSITION AND METHOD FOR FORMING COATING FILM KANSAI PAINT CO., LTD. (JP) 2025-07-24 US disclosed
EP-4481009-A1 COATING COMPOSITION AND METHOD FOR FORMING COATING FILM Kansai Paint Co., Ltd. (JP) 2024-12-25 EP disclosed
WO-2023157942-A1 COATING COMPOSITION AND METHOD FOR FORMING COATING FILM 関西ペイント株式会社 2023-08-24 WO disclosed
EP-3362499-B1 SYSTEMS AND METHODS FOR FORMING POLYURETHANES EASTMAN CHEM CO (US) 2021-09-22 EP disclosed
EP-2762240-B1 METHOD FOR FORMING COATING FILM AND COATED ARTICLE KANSAI PAINT CO LTD (JP) 2020-11-04 EP disclosed
US-10640641-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2020-05-05 US disclosed
WO-2012122098-A1 COMPOSITIONS OF A METAL AMIDINE COMPLEX AND SECOND COMPOUND, COATING COMPOSITIONS COMPRISING SAME KING INDUSTRIES, INC. (US) 2012-09-13 WO disclosed
US-20120225982-A1 COMPOSITIONS OF A METAL AMIDINE COMPLEX AND SECOND COMPOUND, COATING COMPOSITIONS COMPRISING SAME KING INDUSTRIES, INC. 2012-09-06 US disclosed
US-20120070569-A1 ORGANOMETALLIC COMPOSITIONS AND COATING COMPOSITIONS KING INDUSTRIES, INC. (US) 2012-03-22 US disclosed
US-8088846-B2 Organometallic compositions and coating compositions KING INDUSTRIES, INC. (US) 2012-01-03 US disclosed
US-7485729-B2 Complexes of zinc with substituted amidines and guanidines and aliphatic carboxylates, e.g., Zn(1-methylimidazole)2(acetate)2 and Zn(tetramethylguanidine)2(formate)2; useful as catalysts for deblocking blocked isocyanates and in the production of urethanes and polyurethanes KING INDUSTRIES, INC. (US) 2009-02-03 US disclosed
US-20090011124-A1 Complexes of zinc with substituted amidines and guanidines and aliphatic carboxylates, e.g., Zn(1-methylimidazole)2(acetate)2 and Zn(1-methylimidazole)2(2-ethylhexanoate)2; useful as catalysts for deblocking blocked isocyanates and in the production of urethanes and polyurethanes HSIEH BING 2009-01-08 US disclosed
US-20060247341-A1 Complexes of zinc with substituted amidines and guanidines and aliphatic carboxylates, e.g., Zn(1-methylimidazole)2(acetate)2 and Zn(tetramethylguanidine)2(formate)2; useful as catalysts for deblocking blocked isocyanates and in the production of urethanes and polyurethanes KING INDUSTRIES, INC. 2006-11-02 US disclosed
US-20060036007-A1 Organometallic compositions and coating compositions KING INDUSTRIES, INC. (US) 2006-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120070569-A1 ORGANOMETALLIC COMPOSITIONS AND COATING COMPOSITIONS UROD, AOC1, AOC2 TLR8 3186/4885ALDH1A1 1455/4885POLB 2517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.