Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381008 | 0.77 | DCTPP1 (0.51) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14007602 | 0.72 | KDM4E (0.50) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6561604 | 0.72 | KDM4A (0.48) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL6560817 | 0.71 | HSD17B10 (0.57) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14007388 | 0.70 | MGLL (0.49) | KDM4EALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL5753908 | 0.67 | LMNA (0.42) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7957435 | 0.66 | LMNA (0.49) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL16039240 | 0.66 | HSD17B10 (0.53) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16037837 | 0.65 | ALDH1A1 (0.54) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16040772 | 0.65 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009095-B1 | 1.3.4-OXADIAZOLE-2-ONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-13 | — | — | EP | disclosed |
| US-4246403-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |
| EP-0009095-A1 | 1.3.4-Oxadiazole-2-one derivatives, processes for their preparation and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-02 | — | — | EP | disclosed |