Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.56 |
| ▸ | ABAT | P80404 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236745 | 0.77 | MASP2 (0.42) | ALDH5A1ABATMAPTHSD17B10LMNA | |
| SCHEMBL22903637 | 0.77 | CES2 (0.44) | MAPTLMNAMEN1KMT2AALOX15 | |
| SCHEMBL52041 | 0.77 | CES2 (0.44) | MAPTLMNACYP3A4ALOX15CA1 | |
| SCHEMBL8966417 | 0.77 | ALDH1A1 (0.55) | ALDH5A1ABATMAPTHSD17B10ESR1 | |
| SCHEMBL1073763 | 0.77 | ALDH1A1 (0.44) | MAPTHTTLMNAMEN1KMT2A | |
| SCHEMBL18689504 | 0.77 | CES2 (0.44) | MAPTCA1CA2NPC1RAB9A | |
| SCHEMBL3628327 | 0.77 | MAPT (0.52) | ALDH5A1ABATMAPTHSD17B10HTT | |
| SCHEMBL14340575 | 0.77 | MAPT (0.46) | ALDH5A1ABATMAPTHSD17B10HTT | |
| SCHEMBL7190703 | 0.76 | ALDH5A1 (0.58) | ALDH5A1ABATMAPTHSD17B10HTT | |
| SCHEMBL108144 | 0.76 | AKT1 (0.54) | MAPTHSD17B10LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328361-A | Novel process | THE UPJOHN COMPANY (US) | 1982-05-04 | — | — | US | disclosed |