Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325151 | 0.81 | ALOX5 (0.48) | SMN1; SMN2ALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL11335525 | 0.79 | MEN1 (0.56) | KDM4EKMT2AMEN1RECQLSMN1; SMN2 | |
| SCHEMBL11326634 | 0.78 | ALOX5 (0.42) | SMN1; SMN2ALDH1A1TDP1LMNACYP4F2 | |
| SCHEMBL11338014 | 0.78 | SMN1; SMN2 (0.42) | KMT2AMEN1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11323886 | 0.78 | CYP4F2 (0.45) | KMT2ASMN1; SMN2ALDH1A1TDP1CYP4F2 | |
| SCHEMBL11328985 | 0.78 | MEN1 (0.57) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11340956 | 0.78 | SMN1; SMN2 (0.41) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11328407 | 0.76 | ALOX5 (0.42) | KMT2AMEN1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3432284 | 0.74 | ABCB1 (0.50) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL11329177 | 0.74 | KDM4E (0.44) | KDM4EKMT2AMEN1RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006218-B1 | SUBSTITUTED AMINO ACIDS, THEIR USE AND PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-05-26 | — | — | EP | disclosed |
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |
| EP-0006218-A1 | Substituted amino acids, their use and preparation and pharmaceutical compositions containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1980-01-09 | — | — | EP | disclosed |