Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325215 | 0.84 | LTB4R2 (0.41) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11326634 | 0.83 | ALOX5 (0.42) | ALOX5SMN1; SMN2PTPN1CYP4F2CYP4A11 | |
| SCHEMBL11328407 | 0.83 | ALOX5 (0.42) | ALOX5SMN1; SMN2PTPN1CYP4F2CYP4A11 | |
| SCHEMBL11323886 | 0.82 | CYP4F2 (0.45) | ALOX5SMN1; SMN2PTPN1CYP4F2CYP4A11 | |
| SCHEMBL11338014 | 0.81 | SMN1; SMN2 (0.42) | ALOX5SMN1; SMN2PTPN1CYP4F2CYP4A11 | |
| SCHEMBL11296009 | 0.81 | KDM4E (0.40) | ALOX5SMN1; SMN2PTPN1CYP4F2CYP4A11 | |
| SCHEMBL11340956 | 0.80 | SMN1; SMN2 (0.41) | ALOX5SMN1; SMN2PTPN1CYP4F2CYP4A11 | |
| SCHEMBL11322624 | 0.78 | TACR1 (0.43) | ALOX5SMN1; SMN2ALDH1A1GAACYP1A2 | |
| SCHEMBL11328985 | 0.78 | MEN1 (0.57) | ALOX5SMN1; SMN2PTPN1ALDH1A1GAA | |
| SCHEMBL11335525 | 0.75 | MEN1 (0.56) | SMN1; SMN2PTPN1CYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |