Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335525 | 0.97 | MEN1 (0.56) | MEN1KMT2ATSHRALDH1A1NPSR1 | |
| SCHEMBL11330108 | 0.89 | TSHR (0.56) | MEN1KMT2ATSHRALDH1A1NPSR1 | |
| SCHEMBL11300194 | 0.86 | TSHR (0.55) | MEN1KMT2ATSHRALDH1A1NPSR1 | |
| SCHEMBL11328407 | 0.84 | ALOX5 (0.42) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL11338014 | 0.82 | SMN1; SMN2 (0.42) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL11340956 | 0.81 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL11314446 | 0.79 | TSHR (0.51) | MEN1KMT2ATSHRALDH1A1NPSR1 | |
| SCHEMBL11325151 | 0.78 | ALOX5 (0.48) | ALDH1A1SMN1; SMN2GAALMNAALOX5 | |
| SCHEMBL11296009 | 0.78 | KDM4E (0.40) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL11325178 | 0.77 | TSHR (0.58) | MEN1KMT2ATSHRALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |