Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.31 |
| ▸ | INPP5B | P32019 | 1/20 | 0.31 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258267 | 0.77 | LMNA (0.36) | CYP3A4TSHRLMNASMN1; SMN2MAPK1 | |
| SCHEMBL10715975 | 0.72 | AKR1B1 (0.61) | CYP3A4AKR1B1TSHRHPGDHSD17B10 | |
| SCHEMBL29749799 | 0.69 | CYP3A4 (0.50) | CYP3A4AKR1B1TSHRHPGDHSD17B10 | |
| SCHEMBL914797 | 0.69 | CYP3A4 (0.50) | CYP3A4AKR1B1TSHRHPGDHSD17B10 | |
| SCHEMBL25269222 | 0.68 | LMNA (0.33) | CYP3A4LMNASMN1; SMN2MAPK1TDP1 | |
| SCHEMBL28632461 | 0.68 | CYP3A4 (0.43) | CYP3A4AKR1B1TSHRHPGDHSD17B10 | |
| SCHEMBL11230910 | 0.68 | AKR1B1 (0.45) | CYP3A4AKR1B1TSHRHPGDHSD17B10 | |
| SCHEMBL28202875 | 0.68 | CYP3A4 (0.43) | CYP3A4AKR1B1TSHRHPGDHSD17B10 | |
| SCHEMBL28632460 | 0.68 | CYP3A4 (0.43) | CYP3A4AKR1B1TSHRHPGDHSD17B10 | |
| SCHEMBL11599512 | 0.67 | ALOX15 (0.34) | CYP3A4TSHRHSP90AA1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050410-A1 | Method of enhancing flammability resistance of polyparabanic acid films by the addition of copper chelates and films thus formed | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1982-04-28 | — | — | EP | claimed |