SCHEMBL25269222

SCHEMBL25269222

O=P(OCl)(OCl)Oc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FABP3 P05413 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258267 0.90 LMNA (0.36) LMNASMN1; SMN2FABP3MRGPRX4CYP3A4
SCHEMBL11599512 0.82 ALOX15 (0.34) LMNASMN1; SMN2FABP3MRGPRX4CYP3A4
SCHEMBL28458158 0.82 SMN1; SMN2 (0.44) LMNASMN1; SMN2MRGPRX4CYP3A4MAPK1
SCHEMBL31661065 0.79 LMNA (0.35) LMNASMN1; SMN2FABP3MRGPRX4CYP3A4
SCHEMBL30023648 0.78 INPPL1 (0.54) LMNASMN1; SMN2FABP3MRGPRX4CYP3A4
SCHEMBL258268 0.78 INPPL1 (0.54) LMNASMN1; SMN2FABP3MRGPRX4CYP3A4
SCHEMBL10336013 0.74 TDP1 (0.47) LMNASMN1; SMN2MAPK1TDP1
SCHEMBL28200093 0.74 INPPL1 (0.33) LMNASMN1; SMN2FABP3MRGPRX4CYP3A4
SCHEMBL1377763 0.73 LMNA (0.62) LMNASMN1; SMN2MAPK1
SCHEMBL5441328 0.71 SMN1; SMN2 (0.48) LMNASMN1; SMN2MRGPRX4CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230176481-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-06-08 US disclosed