SCHEMBL11599512

SCHEMBL11599512

COP(=O)(OC)Oc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP3A4 P08684 2/20 0.33
TSHR P16473 1/20 0.33
HIF1A Q16665 1/20 0.33
LMNA P02545 4/20 0.33
POLB P06746 2/20 0.33
HTT P42858 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
FABP3 P05413 1/20 0.32
GAA P10253 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
HTR2A P28223 2/20 0.32
HTR2C P28335 2/20 0.32
HTR2B P41595 2/20 0.32
MAPK1 P28482 2/20 0.31
KDM4E B2RXH2 1/20 0.31
S1PR4 O95977 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258267 0.88 LMNA (0.36) CYP3A4TSHRLMNASMN1; SMN2FABP3
SCHEMBL25269222 0.82 LMNA (0.33) CYP3A4LMNASMN1; SMN2FABP3MRGPRX4
SCHEMBL31661065 0.78 LMNA (0.35) CYP3A4LMNASMN1; SMN2FABP3MRGPRX4
SCHEMBL11602041 0.77 TDP1 (0.42) ALDH1A1CYP3A4TSHRLMNAPOLB
SCHEMBL258268 0.76 INPPL1 (0.54) ALDH1A1CYP3A4LMNASMN1; SMN2FABP3
SCHEMBL30023648 0.76 INPPL1 (0.54) ALDH1A1CYP3A4LMNASMN1; SMN2FABP3
SCHEMBL3222697 0.74 LMNA (0.60) TSHRLMNAPOLBSMN1; SMN2GAA
SCHEMBL15656094 0.72 ALDH1A1 (0.46) ALOX15ALDH1A1CYP3A4TSHRHIF1A
SCHEMBL30715275 0.72 ALDH1A1 (0.46) ALDH1A1CYP3A4LMNAPOLBHTT
SCHEMBL53547 0.72 ALDH1A1 (0.46) ALDH1A1CYP3A4LMNAPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4067927-A TEXTILES STAUFFER CHEMICAL COMPANY (US) 1978-01-10 US disclosed
US-4017257-A Textiles fire-retardant treated with copolycondensed vinylphosphonates and process STAUFFER CHEMICAL COMPANY (US) 1977-04-12 US disclosed