Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11297048 | 0.82 | RAD52 (0.43) | POLBKMT2AMEN1MAPK1GAA | |
| SCHEMBL11297617 | 0.78 | MAOB (0.42) | POLBKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL11287307 | 0.77 | MAOB (0.44) | POLBKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL11295491 | 0.70 | MTNR1A (0.36) | OPRM1 | |
| SCHEMBL11544999 | 0.68 | AKR1C1 (0.37) | KMT2AMEN1GAASMN1; SMN2HTT | |
| SCHEMBL11289721 | 0.66 | ALDH1A1 (0.42) | KMT2AMAPK1GAAALDH1A1KDM4E | |
| SCHEMBL11289410 | 0.64 | — | — | |
| SCHEMBL11503128 | 0.64 | SLC6A2 (0.31) | SLC6A2SLC6A3 | |
| SCHEMBL11295572 | 0.64 | LMNA (0.37) | KMT2ALMNACYP1A2CYP2C19 | |
| SCHEMBL11290081 | 0.64 | IDO1 (0.32) | SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000825-B1 | GEMINALLY DISUBSTITUTED INDENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Kabi AB (SE) | 1982-04-14 | — | — | EP | disclosed |