Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17690008 | 0.78 | CHRNB2 (0.32) | — | |
| SCHEMBL28935579 | 0.77 | CYP11B1 (0.40) | HTR2A | |
| SCHEMBL30616031 | 0.77 | CYP11B1 (0.40) | HTR2A | |
| SCHEMBL4273014 | 0.77 | HTR2A (0.38) | HTR2A | |
| SCHEMBL10827811 | 0.77 | HTR2A (0.38) | HTR2A | |
| SCHEMBL7046660 | 0.77 | HTR2A (0.38) | HTR2A | |
| SCHEMBL18064744 | 0.75 | CYP2A6 (0.32) | — | |
| SCHEMBL12483814 | 0.74 | PTGDR2 (0.34) | HTR2A | |
| SCHEMBL6247077 | 0.74 | HTR2A (0.36) | HTR2A | |
| SCHEMBL7608274 | 0.74 | HTR2A (0.37) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11980598-B2 | N-(2-(substituted-naphth-1-yl)ethyl) substituted amide compound, preparation and uses thereof | BEIJING GREATWAY PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2024-05-14 | — | — | US | claimed |
| US-20210077431-A1 | N-(2-(SUBSTITUTED-NAPHTH-1-YL)ETHYL) SUBSTITUTED AMIDE COMPOUND, PREPARATION AND USES THEREOF | BEIJING GREATWAY PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2021-03-18 | — | — | US | claimed |
| EP-3653602-A1 | N-(2-(SUBSTITUTED-NAPHTH-1-YL)ETHYL) SUBSTITUTED AMIDE COMPOUND, PREPARATION AND USES THEREOF | Beijing Greatway Pharmaceutical Technology Co., Ltd. (CN) | 2020-05-20 | — | — | EP | claimed |
| US-11980598-B2 | N-(2-(substituted-naphth-1-yl)ethyl) substituted amide compound, preparation and uses thereof | BEIJING GREATWAY PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2024-05-14 | — | — | US | disclosed |
| US-20210077431-A1 | N-(2-(SUBSTITUTED-NAPHTH-1-YL)ETHYL) SUBSTITUTED AMIDE COMPOUND, PREPARATION AND USES THEREOF | BEIJING GREATWAY PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2021-03-18 | — | — | US | disclosed |
| EP-3653602-A1 | N-(2-(SUBSTITUTED-NAPHTH-1-YL)ETHYL) SUBSTITUTED AMIDE COMPOUND, PREPARATION AND USES THEREOF | Beijing Greatway Pharmaceutical Technology Co., Ltd. (CN) | 2020-05-20 | — | — | EP | disclosed |
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11980598-B2 | N-(2-(substituted-naphth-1-yl)ethyl) substituted amide compound, preparation and uses thereof | MTNR1A, HTR2C, MTNR1B | HTR2A 4/4885ATM 3003/4885IDO1 321/4885 |
| US-20210077431-A1 | N-(2-(SUBSTITUTED-NAPHTH-1-YL)ETHYL) SUBSTITUTED AMIDE COMPOUND, PREPARATION AND USES THEREOF | MTNR1A, HTR2C, MTNR1B | HTR2A 4/4885ATM 3003/4885IDO1 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.