Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926615 | 0.89 | SCN4A (0.47) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL2750541 | 0.82 | GRM5 (0.35) | — | |
| SCHEMBL1316597 | 0.80 | RAB9A (0.48) | RAB9AALDH1A1KDM4EARNPC1 | |
| SCHEMBL5541082 | 0.79 | SREBF2 (0.41) | RAB9AALDH1A1KDM4EARNPC1 | |
| SCHEMBL6544558 | 0.79 | MAPT (0.54) | RAB9AALDH1A1KDM4EARNPC1 | |
| SCHEMBL12614991 | 0.79 | CYP1A2 (0.39) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL2753873 | 0.79 | RAB9A (0.44) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL1436055 | 0.79 | KIF11 (0.45) | ALDH1A1KDM4EMEN1KMT2AMAOB | |
| SCHEMBL1201737 | 0.77 | LMNA (0.42) | RAB9AALDH1A1KDM4EARNPC1 | |
| SCHEMBL1436001 | 0.75 | GABRA1 (0.41) | RAB9AARNPC1ALDH1A3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9067930-B2 | 2-oxo-piperidinyl derivatives | UCB PHARMA, S.A. (BE) | 2015-06-30 | — | — | US | claimed |
| EP-2766353-B1 | 2-OXO-PIPERIDINYL DERIVATIVES | UCB PHARMA SA (BE) | 2015-06-17 | — | — | EP | claimed |
| US-20150011526-A1 | 2-Oxo-Piperidinyl Derivatives | UCB BIOPHARMA SPRL (BE) | 2015-01-08 | — | — | US | claimed |
| EP-2766353-A1 | 2-OXO-PIPERIDINYL DERIVATIVES | UCB Pharma, S.A. (BE) | 2014-08-20 | — | — | EP | claimed |
| WO-2013053725-A1 | 2-OXO-PIPERIDINYL DERIVATIVES | UCB PHARMA, S.A. (BE) | 2013-04-18 | — | — | WO | claimed |
| US-9067930-B2 | 2-oxo-piperidinyl derivatives | UCB PHARMA, S.A. (BE) | 2015-06-30 | — | — | US | disclosed |
| EP-2766353-B1 | 2-OXO-PIPERIDINYL DERIVATIVES | UCB PHARMA SA (BE) | 2015-06-17 | — | — | EP | disclosed |
| US-20150011526-A1 | 2-Oxo-Piperidinyl Derivatives | UCB BIOPHARMA SPRL (BE) | 2015-01-08 | — | — | US | disclosed |
| EP-2766353-A1 | 2-OXO-PIPERIDINYL DERIVATIVES | UCB Pharma, S.A. (BE) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013053725-A1 | 2-OXO-PIPERIDINYL DERIVATIVES | UCB PHARMA, S.A. (BE) | 2013-04-18 | — | — | WO | disclosed |
| WO-2012098387-A1 | 6, 7-RING-FUSED TRIAZOLO [4, 3 - B] PYRIDAZINE DERIVATIVES AS PIM INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011526-A1 | 2-Oxo-Piperidinyl Derivatives | CYP3A4, CYP2C19, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | GRM2 2693/4885RAB9A 872/4885ALDH1A1 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.