Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 3/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295620 | 0.76 | FAAH (0.34) | KDM5AKDM4C | |
| SCHEMBL11290878 | 0.76 | FAAH (0.34) | KDM5AKDM4C | |
| SCHEMBL11008999 | 0.72 | CA12 (0.39) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL9666761 | 0.71 | CA1 (0.38) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL11295513 | 0.69 | ACE2 (0.33) | CA1KDM4C | |
| SCHEMBL3062027 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL6274244 | 0.64 | CA12 (0.34) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL11288849 | 0.63 | CES2 (0.40) | CA12CA1CA9 | |
| SCHEMBL109625 | 0.63 | — | — | |
| SCHEMBL7452802 | 0.62 | HSP90AA1 (0.45) | CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311647-A | Process for preparation of (hydrocarbonthio)oxamides | THE B. F. GOODRICH COMPANY (US) | 1982-01-19 | — | — | US | disclosed |