Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | CES1 | P23141 | 4/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 3/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290878 | 1.00 | FAAH (0.34) | FAAHCES1CES2THRBGMNN | |
| SCHEMBL11295513 | 0.91 | ACE2 (0.33) | FAAHEPHX1PHF8KDM4CGGPS1 | |
| SCHEMBL11288849 | 0.77 | CES2 (0.40) | FAAHCES1CES2THRBGMNN | |
| SCHEMBL11297531 | 0.76 | CA12 (0.32) | KDM5AKDM4C | |
| SCHEMBL11293412 | 0.76 | CES2 (0.45) | FAAHCES1CES2THRBGMNN | |
| SCHEMBL6274244 | 0.74 | CA12 (0.34) | KDM5AKDM4C | |
| SCHEMBL11679946 | 0.74 | ALDH1A1 (0.41) | FAAHCES1CES2THRBGMNN | |
| SCHEMBL11289701 | 0.73 | CES2 (0.42) | FAAHCES1CES2THRBGMNN | |
| SCHEMBL11288853 | 0.72 | MGLL (0.49) | FAAHCES1CES2THRBGMNN | |
| SCHEMBL7496380 | 0.71 | HSD17B10 (0.44) | CES2THRBGMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311647-A | Process for preparation of (hydrocarbonthio)oxamides | THE B. F. GOODRICH COMPANY (US) | 1982-01-19 | — | — | US | disclosed |