Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 8/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955245 | 1.00 | ABCB11 (0.78) | ABCB11LMNAMAPTMAPK1HRH2 | |
| SCHEMBL14769764 | 0.90 | MAPT (0.82) | ABCB11LMNAMAPTMAPK1HTT | |
| SCHEMBL11288224 | 0.89 | MAPT (0.80) | ABCB11LMNAMAPTMAPK1HRH2 | |
| Rac-Etomoxir SCHEMBL15256787 | 0.88 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1HRH2 | |
| Rac-Etomoxir SCHEMBL681359 | 0.88 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1HRH2 | |
| SCHEMBL954683 | 0.88 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1HRH2 | |
| Etomoxir SCHEMBL49075 | 0.88 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1HRH2 | |
| SCHEMBL1578568 | 0.88 | MAPT (0.78) | ABCB11LMNAMAPTMAPK1HRH2 | |
| SCHEMBL11292121 | 0.88 | MAPT (0.78) | ABCB11LMNAMAPTMAPK1KDM4E | |
| SCHEMBL957321 | 0.88 | MAPT (0.78) | ABCB11LMNAMAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |