Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298063 | 1.00 | TRPA1 (0.36) | TRPA1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4909272 | 0.75 | TRPA1 (0.41) | TRPA1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1954384 | 0.69 | TRPA1 (0.39) | TRPA1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL14529115 | 0.67 | NOS3 (0.38) | TRPA1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30218263 | 0.66 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL29394860 | 0.66 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL323897 | 0.65 | TRPA1 (0.39) | TRPA1 | |
| SCHEMBL11443029 | 0.65 | TRPA1 (0.36) | TRPA1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11443028 | 0.65 | TRPA1 (0.36) | TRPA1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3104571 | 0.64 | TRPA1 (0.42) | TRPA1NPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4238607-A | ANTIBIOTICS, SEDATIVES, HYPOTENSIVE AGENTS, AND ANTIDEPRESSANTS | ENDO LABORATORIES INC. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4183936-A | SEDATIVES, ANTIDEPRESSANTS, HYPOTENSIVE AGENTS, BACTERICIDES | ENDO LABORATORIES, INC. (US) | 1980-01-15 | — | — | US | disclosed |
| US-4115577-A | SEDATIVES, ANTIDEPRESSANT ANTIHYPERTENSIVE, ANTIBACTERIAL | ENDO LABORATORIES, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4013652-A | SEDATIVES | ENDO LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | disclosed |