Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130476 | 0.78 | CRHBP (0.56) | TSHRCRHBPCRHR2SMN1; SMN2GAA | |
| SCHEMBL3507290 | 0.78 | LMNA (0.58) | TSHRPDCD1CD274SMN1; SMN2CHRNB2 | |
| SCHEMBL874377 | 0.78 | TSHR (0.46) | TSHRPDCD1CD274SMN1; SMN2GAA | |
| SCHEMBL2532016 | 0.77 | TSHR (0.42) | TSHRPDCD1CD274SMN1; SMN2GAA | |
| SCHEMBL829848 | 0.76 | TSHR (0.44) | TSHRPDCD1CD274SMN1; SMN2GAA | |
| SCHEMBL29025475 | 0.76 | ALDH1A1 (0.54) | TSHRPDCD1CD274SMN1; SMN2GAA | |
| SCHEMBL10868714 | 0.76 | TSHR (0.41) | TSHRPDCD1CD274SMN1; SMN2GAA | |
| SCHEMBL28268442 | 0.76 | CRHBP (0.44) | TSHRCRHBPCRHR2SMN1; SMN2GAA | |
| SCHEMBL6182625 | 0.75 | CRHBP (0.41) | TSHRCRHBPCRHR2SMN1; SMN2NPSR1 | |
| SCHEMBL7293158 | 0.75 | ALDH1A1 (0.49) | TSHRCRHBPCRHR2SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261732-A | Alkyl and alkoxyalkyl N-3-alkyl and N-3,5-dialkylbenzoyl-N-isopropylaminoacetate herbicides | PPG INDUSTRIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4197114-A | Alkyl N-3-alkoxy-, and N-3,5-dialkoxybenzoyl-N-isopropylaminoacetate herbicides | PPG INDUSTRIES, INC. (US) | 1980-04-08 | — | — | US | disclosed |