Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | NMT2 | O60551 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300971 | 0.84 | S1PR2 (0.36) | FPR2S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL11306079 | 0.83 | MMP1 (0.34) | FPR2S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL11303147 | 0.81 | S1PR2 (0.33) | FPR2S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL11302281 | 0.78 | REN (0.34) | S1PR2S1PR1S1PR3S1PR4FDPS | |
| SCHEMBL11306896 | 0.78 | S1PR2 (0.33) | FPR2S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL11298731 | 0.78 | S1PR2 (0.33) | S1PR2S1PR1S1PR3S1PR4FDPS | |
| SCHEMBL11298205 | 0.78 | DPP7 (0.43) | FPR2CTSSCTSKFDPS | |
| SCHEMBL17323294 | 0.77 | CTSS (0.37) | FPR2CTSSCTSK | |
| SCHEMBL11296863 | 0.76 | ENPEP (0.34) | S1PR2S1PR1S1PR3S1PR4MMP1 | |
| SCHEMBL11304056 | 0.76 | ENPEP (0.35) | S1PR2S1PR1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002822-A1 | Phosphorus containing peptide derivatives, their production, intermediates for their production and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-11 | — | — | EP | claimed |
| EP-0002822-B1 | PHOSPHORUS CONTAINING PEPTIDE DERIVATIVES, THEIR PRODUCTION, INTERMEDIATES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-07-28 | — | — | EP | disclosed |
| EP-0026409-A1 | Combinations of active ingredients, pharmaceutical preparations, as well as their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-08 | — | — | EP | disclosed |
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |
| EP-0002822-A1 | Phosphorus containing peptide derivatives, their production, intermediates for their production and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-11 | — | — | EP | disclosed |