Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298293 | 1.00 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL11442922 | 0.82 | DHODH (0.47) | ALDH1A1RAB9ANPC1GAADHODH | |
| SCHEMBL11442923 | 0.82 | DHODH (0.47) | ALDH1A1RAB9ANPC1GAADHODH | |
| SCHEMBL11442924 | 0.82 | DHODH (0.47) | ALDH1A1RAB9ANPC1GAADHODH | |
| SCHEMBL20552543 | 0.78 | RAB9A (0.41) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL13185291 | 0.75 | ALDH1A1 (0.45) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL11301345 | 0.75 | TP53 (0.43) | ALDH1A1RAB9ASMN1; SMN2GAAMAOB | |
| SCHEMBL11301348 | 0.75 | TP53 (0.43) | ALDH1A1RAB9ASMN1; SMN2GAAMAOB | |
| SCHEMBL5691682 | 0.75 | PTPN1 (0.52) | ALDH1A1RAB9ASMN1; SMN2MAPK1CXCL8 | |
| SCHEMBL11299981 | 0.74 | MAOB (0.46) | RAB9AGAADHODHMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254048-A | ANTIINFLAMMATORY AGENTS; FOR ARTHRITIS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | claimed |