SCHEMBL11298327

SCHEMBL11298327

[C-]#[N+]C(CCC)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
ZDHHC7 Q9NXF8 1/20 0.40
HDAC7 Q8WUI4 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
TAS1R3 Q7RTX0 5/20 0.34
TAS1R1 Q7RTX1 5/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
SLC6A3 Q01959 2/20 0.33
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29950515 0.88 CA2 (0.53) CA1CA2ZDHHC7TAS1R3TAS1R1
SCHEMBL29955967 0.85 CA1 (0.39) CA1CA2ZDHHC7SMN1; SMN2TSHR
SCHEMBL29956933 0.85 ZDHHC7 (0.56) CA1CA2ZDHHC7ABCB1KMT2A
SCHEMBL9832435 0.83
SCHEMBL29956277 0.80 GABRP (0.38) CA1CA2TSHRKMT2A
SCHEMBL29951369 0.79 CA1 (0.32) CA1CA2ZDHHC7SMN1; SMN2
SCHEMBL29950857 0.79 CA1 (0.35) CA1CA2ZDHHC7SMN1; SMN2
SCHEMBL29956397 0.79 L3MBTL1 (0.41) TAS1R3TAS1R1CYP3A4KMT2AUSP2
SCHEMBL29956292 0.78
SCHEMBL29668156 0.77 ZDHHC7 (0.36) CA1CA2ZDHHC7USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-4261731-A Alpha-isocyano-carboxylic acid amide compounds and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1981-04-14 US disclosed