SCHEMBL29955967

SCHEMBL29955967

[C-]#[N+]C(CCCC([N+]#[C-])C(=O)OC)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ZDHHC7 Q9NXF8 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.34
KMT2A Q03164 2/20 0.32
TSHR P16473 1/20 0.31
CA14 Q9ULX7 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29950515 0.90 CA2 (0.53) CA1CA2ZDHHC7TSHR
SCHEMBL29950857 0.88 CA1 (0.35) CA1CA2ZDHHC7SMN1; SMN2
SCHEMBL29668156 0.87 ZDHHC7 (0.36) CA1CA2ZDHHC7
SCHEMBL29956933 0.87 ZDHHC7 (0.56) CA1CA2ZDHHC7KMT2A
SCHEMBL29952883 0.87 TSHR (0.48) CA1CA2KMT2ATSHR
SCHEMBL11298327 0.85 CA1 (0.42) CA1CA2ZDHHC7SMN1; SMN2KMT2A
SCHEMBL29956277 0.82 GABRP (0.38) CA1CA2KMT2ATSHR
SCHEMBL29951369 0.80 CA1 (0.32) CA1CA2ZDHHC7SMN1; SMN2ESR1
SCHEMBL29956397 0.80 L3MBTL1 (0.41) KMT2A
SCHEMBL9832435 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed