Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271630 | 0.85 | POLB (0.41) | MEN1KMT2ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL11298574 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2ANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11297916 | 0.75 | NPSR1 (0.43) | MEN1KMT2ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL11770016 | 0.74 | KMT2A (0.41) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11253758 | 0.73 | KMT2A (0.34) | MEN1KMT2ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL27430913 | 0.70 | ICAM1 (0.37) | SMN1; SMN2TSHRALDH1A1MCHR1L3MBTL1 | |
| SCHEMBL31319100 | 0.70 | TSHR (0.43) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 | |
| Bicarbonate SCHEMBL31082134 | 0.70 | L3MBTL1 (0.45) | SMN1; SMN2TSHRL3MBTL1POLBCA12 | |
| Oxalic Acid SCHEMBL31082143 | 0.69 | L3MBTL1 (0.44) | SMN1; SMN2TSHRL3MBTL1POLBCA12 | |
| SCHEMBL11299784 | 0.68 | ALDH1A1 (0.41) | MEN1KMT2ANPSR1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311647-A | Process for preparation of (hydrocarbonthio)oxamides | THE B. F. GOODRICH COMPANY (US) | 1982-01-19 | — | — | US | disclosed |