SCHEMBL11298577

SCHEMBL11298577

O=C(NNC(=S)NNC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.75
GAA P10253 6/20 0.75
NPC1 O15118 5/20 0.75
ALDH1A1 P00352 3/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
CCR6 P51684 1/20 0.66
POLB P06746 1/20 0.64
CTDSP1 Q9GZU7 1/20 0.63
KDM4E B2RXH2 1/20 0.61
ALPL P05186 1/20 0.60
ALPI P09923 1/20 0.60
ALPG P10696 1/20 0.60
CYP2C9 P11712 1/20 0.60
CA1 P00915 1/20 0.59
CA9 Q16790 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11599578 0.90 KMT2A (0.86) RAB9AGAANPC1ALDH1A1SMN1; SMN2
SCHEMBL400890 0.88 RAB9A (0.77) RAB9AGAANPC1ALDH1A1SMN1; SMN2
SCHEMBL8719394 0.88 RAB9A (0.66) RAB9AGAANPC1ALDH1A1SMN1; SMN2
SCHEMBL9220486 0.88 RAB9A (0.67) RAB9AGAANPC1ALDH1A1SMN1; SMN2
SCHEMBL6967578 0.86 RAB9A (0.63) RAB9AGAANPC1ALDH1A1SMN1; SMN2
SCHEMBL13547676 0.86 GAA (1.00) RAB9AGAANPC1ALDH1A1SMN1; SMN2
SCHEMBL12324391 0.85 RAB9A (0.82) RAB9AGAANPC1ALDH1A1SMN1; SMN2
SCHEMBL6967575 0.84 RAB9A (0.61) RAB9AGAANPC1ALDH1A1SMN1; SMN2
SCHEMBL9825195 0.84 RAB9A (0.61) RAB9AGAANPC1ALDH1A1SMN1; SMN2
SCHEMBL31558731 0.83 KMT2A (0.72) RAB9AGAANPC1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0002763-B1 PHOTOGRAPHIC MATERIAL WITH STABILISERS AND REVERSAL PROCESS FOR PRODUCING A PHOTOGRAPH Agfa-Gevaert AG (DE) 1982-02-03 EP disclosed
US-4282313-A Photographic material with stabilizers AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1981-08-04 US disclosed
EP-0002763-A2 Photographic material with stabilisers and reversal process for producing a photograph Agfa-Gevaert AG (DE) 1979-07-11 EP disclosed