Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | CCR6 | P51684 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400890 | 0.88 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11298577 | 0.86 | RAB9A (0.75) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL12324391 | 0.85 | RAB9A (0.82) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6967575 | 0.84 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9825195 | 0.84 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| Malonic Acid SCHEMBL30274338 | 0.84 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11814217 | 0.83 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL37273 | 0.83 | ALDH1A1 (0.68) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3724445 | 0.81 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28875360 | 0.81 | SMN1; SMN2 (0.71) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |