Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.52 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.52 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.52 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11296130 | 0.98 | SENP3 (0.51) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL483895 | 0.85 | LMNA (0.45) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL3308193 | 0.84 | SENP3 (0.62) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL3308195 | 0.84 | SENP3 (0.62) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL10907360 | 0.84 | P2RY6 (0.51) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL4631228 | 0.84 | P2RY6 (0.51) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL10907353 | 0.82 | SENP3 (0.50) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL1772255 | 0.81 | CYP3A4 (0.42) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL6313736 | 0.81 | CA2 (0.40) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL241807 | 0.81 | CA2 (0.60) | CA2CA9GLO1CA12NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325887-A | Isocyanatoaryl sulfonic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4259255-A | ISOCYANATOARYL SULFONATES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-31 | — | — | US | disclosed |