SCHEMBL6313736

SCHEMBL6313736

O=C=Nc1cccc(S(=O)(=O)F)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.40
CA9 Q16790 7/20 0.40
CA12 O43570 3/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GLO1 Q04760 4/20 0.39
CYP3A4 P08684 3/20 0.38
TRPA1 O75762 1/20 0.38
NOS1 P29475 1/20 0.38
CA7 P43166 4/20 0.37
CA1 P00915 4/20 0.37
SENP3 Q9H4L4 2/20 0.36
SENP2 Q9HC62 2/20 0.36
SENP1 Q9P0U3 2/20 0.36
SUMO2 P61956 1/20 0.36
SUMO1 P63165 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
TSHR P16473 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483895 0.85 LMNA (0.45) CA2CA9CA12MAPK1TDP1
SCHEMBL11298641 0.81 SENP3 (0.52) CA2CA9CA12MAPK1TDP1
SCHEMBL241807 0.81 CA2 (0.60) CA2CA9CA12GLO1NOS1
SCHEMBL11296127 0.81 TDP1 (0.44) CA2CA9CA12MAPK1TDP1
SCHEMBL1772255 0.81 CYP3A4 (0.42) CA2CA9CA12MAPK1TDP1
SCHEMBL4091937 0.81 RAB9A (0.47) CA2CA9CA12
SCHEMBL10450509 0.81 ALDH1A1 (0.42) CA2CA9CA12MAPK1TDP1
Hydrochloric Acid SCHEMBL11296130 0.80 SENP3 (0.51) CA2CA9CA12MAPK1TDP1
SCHEMBL183418 0.80 CA2 (0.39) CA2CA9CA12MAPK1TDP1
SCHEMBL17577475 0.79 MAPK1 (0.42) CA2CA9CA12MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6861523-B2 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 2005-03-01 US disclosed
US-20030186320-A1 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries TORREY PINES INSTITUTE FOR MOLECULAR STUDIES 2003-10-02 US disclosed
EP-0472492-B1 Tris-perfluoroalkyl terminated neopentyl alcohols and derivatives therefrom CIBA GEIGY AG (CH) 1994-10-05 EP disclosed
US-5182336-A Compatibilizing agents, polyphenylene ether, alkenylaromatic polymer, polyamide, lactam SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-01-26 US disclosed
EP-0348350-B1 HETEROATOM CONTAINING PERFLUOROALKYL TERMINATED NEOPENTYL GLYCOLS AND POLYMERS THEREFROM CIBA-GEIGY AG (CH) 1993-01-20 EP disclosed
EP-0472492-A1 Tris-perfluoroalkyl terminated neopentyl alcohols and derivatives therefrom CIBA-GEIGY AG (CH) 1992-02-26 EP disclosed
US-5068397-A Alcohols as intermediates for polyurethanes, polyesters and polycarbonates CIBA-GEIGY CORPORATION (US) 1991-11-26 US disclosed
US-5045624-A Polyesters, Polyurethanes CIBA-GEIGY CORPORATION (US) 1991-09-03 US disclosed
EP-0435504-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-07-03 EP disclosed
US-4946992-A OIL REPELLENT, WATERPROOFING CIBA-GEIGY CORPORATION (US) 1990-08-07 US disclosed
US-4499149-A ADHESION; HEAT RESISTANCE; PROTECTIVE COATINGS; SEMICONDUCTORS; POLYIMIDES M&T CHEMICALS INC. (US) 1985-02-12 US disclosed
US-4480009-A POLYIMIDE, POLYAMIDEIMIDE, OR POLY-HALF-AMIDE M&T CHEMICALS INC. (US) 1984-10-30 US disclosed
EP-0054426-A2 Improvements in or relating to siloxanes M & T CHEMICALS, INC. (US) 1982-06-23 EP disclosed
US-4158672-A OIL AND WATER REPELLENTS FOR TEXTILES CIBA-GEIGY CORPORATION (US) 1979-06-19 US disclosed
US-4108890-A Nitro or amino phenylenebis(carbonylimino)dinaphthalenetrisulfonic compounds as complement inhibitors AMERICAN CYANAMID COMPANY (US) 1978-08-22 US disclosed
US-4097642-A URETHANE-CONTAINING CIBA-GEIGY CORPORATION (US) 1978-06-27 US disclosed
US-4054592-A Urethanes containing two perfluoroalkylthio groups CIBA-GEIGY CORPORATION (US) 1977-10-18 US disclosed
US-4051176-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1977-09-27 US disclosed
US-4001305-A POLYURETHANES, OIL AND WATER REPELLANT, MOLD-RELEASE CIBA-GEIGY CORPORATION (US) 1977-01-04 US disclosed
US-3935277-A OIL AND WATER REPELLENT INTERMEDIATES CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186320-A1 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries CDK15, CUL5, UTS2R CA2 1955/4885CA9 2877/4885CA12 3185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.