Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL956571 | 0.94 | LMNA (0.60) | LMNAABCB11MAPTMAPK1L3MBTL1 | |
| SCHEMBL11290353 | 0.86 | FAAH (0.50) | LMNAABCB11MAPTMAPK1L3MBTL1 | |
| SCHEMBL11289835 | 0.84 | LMNA (0.54) | LMNAABCB11MAPTMAPK1L3MBTL1 | |
| SCHEMBL11020225 | 0.83 | L3MBTL1 (0.47) | LMNAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL11290182 | 0.82 | KDM4E (0.48) | LMNAABCB11MAPTMAPK1L3MBTL1 | |
| SCHEMBL11292129 | 0.82 | LMNA (0.64) | LMNAABCB11MAPTMAPK1KDM4E | |
| SCHEMBL11266840 | 0.82 | THRB (0.47) | LMNAABCB11MAPTMAPK1L3MBTL1 | |
| SCHEMBL11295569 | 0.81 | KDM4E (0.47) | LMNAABCB11MAPTMAPK1L3MBTL1 | |
| SCHEMBL11261814 | 0.80 | MAPT (0.46) | LMNAABCB11MAPTMAPK1KDM4E | |
| SCHEMBL11289517 | 0.80 | MAPK1 (0.58) | LMNAABCB11MAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |