Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | LGMN | Q99538 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306282 | 0.93 | PRSS1 (0.43) | PRSS1TPSAB1LGMNCACNA1HCTSB | |
| SCHEMBL11307649 | 0.92 | LGMN (0.43) | PRSS1TPSAB1LGMNCACNA1HCTSB | |
| SCHEMBL11308607 | 0.88 | CTSK (0.43) | PRSS1TPSAB1CACNA1HMEN1KMT2A | |
| SCHEMBL11303050 | 0.87 | CTSK (0.42) | PRSS1TPSAB1CACNA1H | |
| SCHEMBL11298770 | 0.87 | CPA1 (0.41) | PRSS1TPSAB1LGMNCACNA1HCTSB | |
| SCHEMBL11299562 | 0.85 | REN (0.44) | CACNA1H | |
| SCHEMBL11304447 | 0.85 | CACNA1H (0.41) | PRSS1TPSAB1LGMNCACNA1HCTSB | |
| SCHEMBL11304059 | 0.84 | PRSS1 (0.43) | PRSS1TPSAB1LGMNCACNA1HCTSB | |
| SCHEMBL11304064 | 0.83 | CTSK (0.43) | LGMNCACNA1H | |
| SCHEMBL11297063 | 0.82 | OPRD1 (0.47) | CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |