Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084169 | 0.67 | ALOX5 (0.42) | DDB1CRBNALOX5ALOX12ALOX15 | |
| SCHEMBL10800977 | 0.63 | INMT (0.40) | DDB1CRBNALOX12ALOX15MAPT | |
| SCHEMBL3131857 | 0.62 | CYP19A1 (0.44) | DDB1CRBNALOX5G6PDMAPT | |
| SCHEMBL4712786 | 0.61 | DDB1 (0.56) | DDB1CRBNALOX12ALOX15MAPT | |
| SCHEMBL8077864 | 0.60 | DDB1 (0.39) | DDB1CRBNALOX12ALOX15MAPT | |
| SCHEMBL25846387 | 0.59 | DDB1 (0.60) | DDB1CRBNALOX12ALOX15MAPT | |
| SCHEMBL3035197 | 0.59 | LGMN (0.60) | ALOX12ALOX15MAPTALDH1A1KDM4E | |
| SCHEMBL23347931 | 0.58 | MAPT (0.77) | DDB1CRBNALOX12ALOX15MAPT | |
| SCHEMBL6151120 | 0.58 | MAPT (0.77) | DDB1CRBNALOX12ALOX15MAPT | |
| SCHEMBL7043679 | 0.58 | MAPT (0.77) | DDB1CRBNALOX12ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052442-A1 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-05-26 | — | — | EP | disclosed |