Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 3/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11442973 | 0.86 | PLA2G2A (0.51) | TSHRPLA2G2A | |
| SCHEMBL24675796 | 0.82 | TSHR (0.59) | TSHRDHFRPLA2G4BGGPS1 | |
| SCHEMBL11299159 | 0.81 | HTT (0.41) | TSHRPLA2G2A | |
| SCHEMBL15923537 | 0.81 | TSHR (0.66) | TSHRDHFRPLA2G4BGGPS1PPARG | |
| SCHEMBL9819746 | 0.81 | TSHR (0.66) | TSHRDHFRPLA2G4BGGPS1PPARG | |
| SCHEMBL17402425 | 0.81 | TSHR (0.66) | TSHRDHFRPLA2G4BGGPS1PPARG | |
| SCHEMBL25170047 | 0.81 | TSHR (0.66) | TSHRDHFRPLA2G4BGGPS1PPARG | |
| SCHEMBL15922807 | 0.81 | TSHR (0.66) | TSHRDHFRPLA2G4BGGPS1PPARG | |
| SCHEMBL27345369 | 0.79 | LTA4H (0.50) | TSHRPLA2G2A | |
| SCHEMBL6529839 | 0.79 | TSHR (0.63) | TSHRDHFRPLA2G4BGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262021-A | INDUCERS OF PRODUCTION OF INTERFERON | PFIZER INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4215146-A | Antiviral amine derivatives of glycerol and propanediols | PFIZER INC. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4193999-A | Antiviral amine derivatives of propanediols | PFIZER INC. (US) | 1980-03-18 | — | — | US | disclosed |