Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211934 | 0.80 | SMN1; SMN2 (0.56) | HPGDLMNAFFAR1KMT2AALDH1A1 | |
| SCHEMBL11181823 | 0.76 | LMNA (0.74) | HPGDLMNAFFAR1POLBKMT2A | |
| SCHEMBL9479429 | 0.76 | LMNA (0.74) | HPGDLMNAFFAR1POLBKMT2A | |
| SCHEMBL14426475 | 0.76 | LMNA (0.74) | HPGDLMNAFFAR1KMT2AALDH1A1 | |
| SCHEMBL11188489 | 0.75 | HPGD (0.60) | HPGDLMNAFFAR1POLBKMT2A | |
| SCHEMBL11157512 | 0.73 | ALDH1A1 (0.52) | HPGDPOLBKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL11143093 | 0.71 | ALDH1A1 (0.51) | HPGDLMNAPOLBKMT2AALDH1A1 | |
| SCHEMBL9748851 | 0.71 | HPGD (0.55) | HPGDLMNAFFAR1POLBKMT2A | |
| SCHEMBL10687158 | 0.70 | NPC1 (0.79) | HPGDLMNAPOLBKMT2AALDH1A1 | |
| SCHEMBL10965462 | 0.69 | CA12 (0.70) | HPGDLMNAPOLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325959-A | Hypoglycemic 4-(((1,3,4, thiadiazolyl)thio)methyl)benzoic acids, ester and amides | THE DOW CHEMICAL COMPANY (US) | 1982-04-20 | — | — | US | disclosed |