Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51274 | 0.84 | GAA (0.54) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30655866 | 0.83 | CA2 (0.53) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3894693 | 0.82 | ANPEP (0.51) | MEN1KMT2ANPC1RAB9AANPEP | |
| SCHEMBL38658329 | 0.82 | ANPEP (0.51) | MEN1KMT2ANPC1RAB9AANPEP | |
| SCHEMBL11305194 | 0.80 | GAA (0.50) | MEN1KMT2ANPC1RAB9APTPN1 | |
| SCHEMBL2451174 | 0.79 | SRD5A2 (0.58) | NPC1RAB9ASMN1; SMN2MAPK1GAA | |
| SCHEMBL941698 | 0.78 | CES2 (0.74) | ACHEHSD17B14MEN1KMT2ANPC1 | |
| SCHEMBL30250451 | 0.78 | CES2 (0.74) | ACHEHSD17B14MEN1KMT2ANPC1 | |
| SCHEMBL29613672 | 0.78 | CES2 (0.74) | ACHEHSD17B14MEN1KMT2ANPC1 | |
| SCHEMBL2152353 | 0.78 | ACHE (0.54) | ACHEHSD17B14MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005530-B1 | NEW MERCAPTOPHENYLKETONES AND THEIR USE AS INITIATORS FOR THE PHOTOPOLYMERISATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |
| US-4279721-A | Mercaptophenyl ketones as initiators for the photopolymerization of ethylenically unsaturated compounds | CIBA-GEIGY CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |
| EP-0005530-A1 | New mercaptophenylketones and their use as initiators for the photopolymerisation of ethylenically unsaturated compounds | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |