Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400550 | 1.00 | CYP2C9 (0.36) | CYP2C9CYP2C19L3MBTL1EPHX1MME | |
| SCHEMBL23715624 | 0.90 | ALDH1A1 (0.36) | CCR2LMNAALDH1A1KMT2AHTT | |
| SCHEMBL11394778 | 0.85 | CYP2C9 (0.35) | CYP2C9CYP2C19L3MBTL1EPHX1MME | |
| SCHEMBL1616851 | 0.81 | CCR2 (0.35) | EPHX1CCR2ALDH1A1KMT2A | |
| SCHEMBL14810642 | 0.79 | CYP1A2 (0.41) | CCR2 | |
| SCHEMBL13715122 | 0.75 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1HTT | |
| SCHEMBL10304246 | 0.74 | DRD2 (0.41) | CYP2C9CYP2C19L3MBTL1EPHX1CCR2 | |
| SCHEMBL16788143 | 0.74 | FFAR3 (0.32) | CYP2C19MME | |
| SCHEMBL26670733 | 0.73 | CYP2C19 (0.37) | CYP2C9CYP2C19L3MBTL1MMEALDH1A1 | |
| SCHEMBL13715165 | 0.73 | L3MBTL1 (0.47) | CYP2C19L3MBTL1LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318900-A | STIMULANTS | WILKINSON SWORD LIMITED (GB) | 1982-03-09 | — | — | US | disclosed |
| US-4248859-A | USED IN EDIBLE AND TOPICAL PREPARATIONS | WILKINSON SWORD LIMITED (GB) | 1981-02-03 | — | — | US | disclosed |