Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407967 | 0.94 | TDP1 (0.48) | TDP1L3MBTL1ATMALDH1A1PBRM1 | |
| SCHEMBL27905642 | 0.86 | CES2 (0.55) | TDP1FOLH1 | |
| SCHEMBL29728644 | 0.85 | L3MBTL1 (0.63) | TDP1L3MBTL1ATMALDH1A1PBRM1 | |
| SCHEMBL1815690 | 0.85 | FOLH1 (0.61) | TDP1FOLH1 | |
| SCHEMBL435297 | 0.85 | L3MBTL1 (0.63) | TDP1L3MBTL1ATMALDH1A1PBRM1 | |
| SCHEMBL7394259 | 0.84 | TDP1 (0.61) | TDP1L3MBTL1ATMALDH1A1PBRM1 | |
| SCHEMBL4669025 | 0.84 | TDP1 (0.61) | TDP1L3MBTL1ATMALDH1A1PBRM1 | |
| SCHEMBL5433433 | 0.83 | TDP1 (0.58) | TDP1L3MBTL1ATMALDH1A1SRD5A2 | |
| SCHEMBL3112767 | 0.82 | KEAP1 (0.62) | TDP1L3MBTL1ATMALDH1A1PBRM1 | |
| SCHEMBL10905589 | 0.82 | ATM (0.59) | TDP1L3MBTL1ATMALDH1A1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103044241-A | Synthesis method of m-phenyl formyl phenylacetic acid | CGENE TECH SUZHOU CHINA CO LTD | 2013-04-17 | — | — | CN | claimed |
| CN-105339379-A | Modified glycolipids and methods of making and using the same | VACCINEX INC | 2016-02-17 | — | — | CN | disclosed |
| CN-103228622-A | Agonists of gpr40 | CONNEXIOS LIFE SCIENCES PVT LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-103044241-A | Synthesis method of m-phenyl formyl phenylacetic acid | CGENE TECH SUZHOU CHINA CO LTD | 2013-04-17 | — | — | CN | disclosed |
| CN-1115320-C | Process for synthesizing ketoibuprofen | UNIV FUDAN (CN) | 2003-07-23 | — | — | CN | disclosed |
| CN-1311779-A | Succinoylamino lactams as inhibitors and as A beta protein production | DU PONT PHARM CO (US) | 2001-09-05 | — | — | CN | disclosed |
| CN-1257860-A | Process for synthesizing ketoibuprofen | UNIV FUDAN (CN) | 2000-06-28 | — | — | CN | disclosed |
| EP-0052311-A1 | 1-((Benzoylphenyl) - lower-alkyl) piperidines and carbinol analogs and preparation thereof | STERLING DRUG INC. (US) | 1982-05-26 | — | — | EP | disclosed |