Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.44 |
| ▸ | FDPS | P14324 | 4/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300949 | 0.72 | BHMT (0.33) | METAP1 | |
| SCHEMBL30312063 | 0.70 | GRIK1 (0.49) | LAP3 | |
| SCHEMBL18251513 | 0.67 | GRIK1 (0.43) | LAP3 | |
| SCHEMBL7814294 | 0.67 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL625939 | 0.67 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| Tuaminoheptane SCHEMBL28624951 | 0.67 | OPRM1 (0.73) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL30759342 | 0.66 | DPP7 (0.46) | METAP1 | |
| Phosphoric Acid SCHEMBL17455469 | 0.66 | LAP3 (0.52) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL7795517 | 0.66 | LAP3 (0.52) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL1060233 | 0.65 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026867-A1 | Peptidylphosphonic acids, their preparation and use, and pharmaceutical preparations containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-15 | — | — | EP | claimed |
| EP-0026867-A1 | Peptidylphosphonic acids, their preparation and use, and pharmaceutical preparations containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-15 | — | — | EP | disclosed |