Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080612 | 0.87 | CA1 (0.38) | POLBCA1CA2MMP1MMP2 | |
| SCHEMBL11313797 | 0.85 | HSD17B10 (0.37) | POLBTSHRMAPK1CA1CA2 | |
| SCHEMBL4665308 | 0.84 | MAPT (0.45) | POLBTSHRMAPK1CA1CA2 | |
| SCHEMBL6935513 | 0.81 | ALDH1A1 (0.37) | TSHRALDH1A1HTTTHRBTP53 | |
| SCHEMBL1568905 | 0.81 | CA1 (0.55) | POLBTSHRMAPK1CA1CA2 | |
| SCHEMBL7074262 | 0.80 | HTR6 (0.40) | POLBMMP1MMP8MMP13F2 | |
| SCHEMBL9457190 | 0.78 | ALDH1A1 (0.36) | TSHRCA2F2PRSS1PRSS2 | |
| SCHEMBL25987068 | 0.78 | ALDH1A1 (0.33) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8663014 | 0.78 | CA2 (0.47) | POLBTSHRCA1CA2L3MBTL1 | |
| SCHEMBL8951838 | 0.78 | CA2 (0.48) | CA1CA2GAACA5ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283196-A | FIXING BY ACTION OF AN ALKALINE AGENT | AMERICAN HOECHST CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |