SCHEMBL4665308

SCHEMBL4665308

COc1cc(S(=O)(=O)CCOS(=O)(=O)O)ccc1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.45
HTT P42858 2/20 0.42
ALDH1A1 P00352 4/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP13 P45452 1/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
F2 P00734 3/20 0.41
PRSS1 P07477 3/20 0.41
PRSS2 P07478 3/20 0.41
PRSS3 P35030 3/20 0.41
POLB P06746 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1568905 0.89 CA1 (0.55) MAPTHTTALDH1A1CA1CA2
SCHEMBL11304856 0.87 ALDH1A1 (0.49) MAPTHTTALDH1A1CA1CA2
SCHEMBL9499213 0.84 CA2 (0.49) MAPTHTTALDH1A1CA1CA2
SCHEMBL11304535 0.84 POLB (0.35) HTTALDH1A1CA1CA2MMP1
SCHEMBL8817851 0.83 CA2 (0.47) MAPTHTTALDH1A1CA1CA2
SCHEMBL28985027 0.83 CA2 (0.46) MAPTHTTALDH1A1CA1CA2
SCHEMBL8080612 0.83 CA1 (0.38) HTTALDH1A1CA1CA2MMP1
SCHEMBL10658602 0.83 CA1 (0.49) MAPTHTTALDH1A1CA1CA2
SCHEMBL8018573 0.82 ALDH1A1 (0.44) MAPTHTTALDH1A1CA1CA2
SCHEMBL7621250 0.81 GAA (0.36) MAPTHTTALDH1A1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7439340-B2 For exhaust dyeing, cold batch-up dyeing and continuous dyeing EVERLIGHT USA, INC. (US) 2008-10-21 US disclosed
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 US disclosed
US-20080039614-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-02-14 US disclosed
EP-1887046-A2 Reactive dyes containing an alkylthio-s-triazinyl reactive group Everlight USA, Inc. (US) 2008-02-13 EP disclosed
US-6809187-B2 FIBER REACTIVE COPPER, COBALT OR CHROMIUM CHELATES; LIGHT-FASTNESS; EFFICIENT UNFIXED MATERIAL WASHOFF OYSTAR TEXTIL FARBEN GMBH & CO. (DE) 2004-10-26 US disclosed
US-20040054154-A1 Metal complex dyes based bucherered naphthols DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2004-03-18 US disclosed
US-6670457-B2 Use for dyeing or printing textile fibre materials CIBA SPECIALTY CHEMICALS CORPORATION 2003-12-30 US disclosed
EP-1090962-B1 Dye mixtures of fiber-reactive azo dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-05-14 EP disclosed
US-20030055230-A1 Reactive dyes, their preparation and use HUNTSMAN INTERNATIONAL LLC 2003-03-20 US disclosed
EP-0979848-B1 Orange dye mixtures of fiber-reactive azo dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-04-17 EP disclosed
EP-0279351-A2 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-24 EP disclosed
US-4757136-A Water-soluble Azo compounds containing fiber-reactive groups and having a sulfo-naphthol coupling component with a triazinylamino substituent suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-12 US disclosed
US-4754023-A Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member CIBA-GEIGY CORPORATION (US) 1988-06-28 US disclosed
US-4740592-A Water-soluble azo compounds containing fiber-reactive groups and having a sulfo-naphthal coupling component with a triazinylamino substituent suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-26 US disclosed
EP-0242850-A1 Water soluble monoazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-28 EP disclosed
US-4703112-A COLOR FASTNESS, ACID RESISTANCE HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-27 US disclosed
EP-0231836-A2 Water soluble disazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-08-12 EP disclosed
US-4652634-A Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-24 US disclosed
US-4576755-A Water-soluble fibre-reactive phthalocyanine compounds HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-18 US disclosed
US-4430259-A Water-soluble disazo compounds suitable as fiber-reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1984-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group TST, IK, NOX5 MAPT 663/4885HTT 953/4885ALDH1A1 393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.