Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23559726 | 0.81 | TDP1 (0.42) | TDP1MAPK1CDK1CCNB1CCNA2 | |
| SCHEMBL11274411 | 0.78 | ESR1 (0.39) | MAPK1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL21876011 | 0.78 | TDP1 (0.44) | TDP1MAPK1CDK1CCNB1CCNA2 | |
| SCHEMBL23689846 | 0.75 | ALOX5 (0.42) | TDP1MAPK1CDK1CCNB1CCNA2 | |
| SCHEMBL11283941 | 0.74 | TLR7 (0.35) | MAPK1HTT | |
| SCHEMBL8384756 | 0.73 | ALOX5 (0.47) | TDP1MAPK1CDK1CCNB1CCNA2 | |
| SCHEMBL10203001 | 0.73 | RAB9A (0.45) | TDP1MAPK1CDK1CCNB1CCNA2 | |
| SCHEMBL11270818 | 0.72 | LTA4H (0.42) | MAPK1ESR1RAB9A | |
| SCHEMBL8384828 | 0.72 | CDK1 (0.41) | TDP1MAPK1CDK1CCNB1CCNA2 | |
| SCHEMBL23567576 | 0.72 | CDK1 (0.36) | TDP1MAPK1CDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320126-A | INSECTICIDES, MITICIDES, NEMATOCIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-16 | — | — | US | disclosed |