Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382888 | 0.88 | PPARG (0.42) | ALOX5PPARGGABRPGABRDGABRA1 | |
| SCHEMBL10203001 | 0.80 | RAB9A (0.45) | ALOX5PPARGGABRPGABRDGABRA1 | |
| SCHEMBL23559726 | 0.79 | TDP1 (0.42) | ALOX5PPARGTLR8TDP1MCHR1 | |
| SCHEMBL4278660 | 0.77 | ALDH1A1 (0.41) | ALOX5PPARGGABRPGABRDGABRA1 | |
| SCHEMBL21876011 | 0.76 | TDP1 (0.44) | ALOX5PPARGTLR8TDP1MCHR1 | |
| SCHEMBL17127911 | 0.76 | NOS3 (0.41) | ALOX5PPARGGABRPGABRDGABRA1 | |
| SCHEMBL8383704 | 0.75 | — | — | |
| SCHEMBL4264141 | 0.75 | MEN1 (0.43) | ALOX5PPARGGABRPGABRDGABRA1 | |
| SCHEMBL8386250 | 0.74 | ALOX5 (0.43) | ALOX5PPARGGABRPGABRDGABRA1 | |
| SCHEMBL16464168 | 0.74 | CDK1 (0.46) | ALOX5PPARGGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565488-B1 | Fluorine free titanocenes and their application | CIBA GEIGY AG (CH) | 1999-04-21 | — | — | EP | disclosed |
| US-5340701-A | Photoinitiators | CIBA-GEIGY CORPORATION (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0565488-A1 | Fluorine free titanocenes and their application | CIBA-GEIGY AG (CH) | 1993-10-13 | — | — | EP | disclosed |