Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ACR | P10323 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | C1R | P00736 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311435 | 0.88 | MAPT (0.60) | SMN1; SMN2MAPTACRPRSS1KMT2A | |
| SCHEMBL11308024 | 0.88 | MAPT (0.62) | SMN1; SMN2MAPTACRPRSS1KMT2A | |
| SCHEMBL11302909 | 0.84 | ALDH1A1 (0.51) | SMN1; SMN2MAPTACRPRSS1KMT2A | |
| SCHEMBL11305611 | 0.83 | MAPK1 (0.52) | SMN1; SMN2MAPTACRPRSS1KMT2A | |
| SCHEMBL11310818 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTACRPRSS1KMT2A | |
| SCHEMBL11308308 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL11312223 | 0.82 | MAPK1 (0.50) | SMN1; SMN2MAPTACRPRSS1KMT2A | |
| SCHEMBL4214461 | 0.82 | PLG (0.56) | SMN1; SMN2ACRPRSS1KMT2AMEN1 | |
| SCHEMBL11304151 | 0.81 | ACR (0.48) | SMN1; SMN2MAPTACRPRSS1KMT2A | |
| SCHEMBL11302014 | 0.80 | CA9 (0.55) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283418-A | ANTIPLASMIN AND ANTITRYPSIN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |