SCHEMBL11307359

SCHEMBL11307359

C[C@H](NC(=O)CNC(=O)OCc1ccccc1Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)P(=O)(O)O

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.41
CYP3A4 P08684 1/20 0.41
HRH1 P35367 1/20 0.41
MME P08473 1/20 0.39
ECE1 P42892 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11305760 0.79 CTSK (0.56) MMEECE1
SCHEMBL11568471 0.77 CTSK (0.57) MMEECE1
SCHEMBL11567663 0.77 CTSK (0.57) MMEECE1
SCHEMBL11030901 0.77 CTSK (0.57) MMEECE1
SCHEMBL11299927 0.76 CTSK (0.53) MMP3
SCHEMBL11298100 0.75 MEN1 (0.44) MMP3
SCHEMBL11297116 0.75 CTSK (0.52) MMP3
SCHEMBL11298733 0.74 PRSS1 (0.44) CYP3A4
SCHEMBL30576721 0.73 TPSAB1 (0.60) CYP3A4
SCHEMBL11112981 0.73 CYP3A4 (0.53) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4250085-A PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES HOFFMANN-LA ROCHE INC. (US) 1981-02-10 US disclosed