Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tiaramide SCHEMBL29376518 | 0.82 | NPY5R (0.58) | TMEM97NPY5RTSHRNPSR1 | |
| Tiaramide SCHEMBL25172 | 0.82 | NPY5R (0.58) | TMEM97NPY5RTSHRNPSR1 | |
| Tiaramide SCHEMBL29379184 | 0.81 | NPY5R (0.58) | TMEM97NPY5RTSHRNPSR1 | |
| Tiaramide SCHEMBL181916 | 0.81 | NPY5R (0.58) | TMEM97NPY5RTSHRNPSR1 | |
| SCHEMBL11308376 | 0.79 | TMEM97 (0.57) | TMEM97ALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL250168 | 0.77 | HSD17B10 (0.42) | ALDH1A1HPGDHSD17B10ALPLMAPT | |
| SCHEMBL11440143 | 0.74 | TMEM97 (0.47) | TMEM97NPY5RMAPTTSHRMAPK1 | |
| SCHEMBL11406400 | 0.74 | NPY5R (0.47) | TMEM97ALDH1A1HPGDHSD17B10NPY5R | |
| SCHEMBL10974768 | 0.73 | TMEM97 (0.47) | TMEM97ALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL13696444 | 0.72 | NPY5R (0.61) | TMEM97NPY5RTSHRNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | claimed |
| CN-100496607-C | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2009-06-10 | — | — | CN | disclosed |
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | disclosed |