Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926603 | 0.84 | AGER (0.48) | CYP19A1POLB | |
| SCHEMBL11307479 | 0.78 | CYP19A1 (0.43) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11322964 | 0.78 | PGR (0.68) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL11307591 | 0.77 | NAMPT (0.41) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11632519 | 0.76 | CYP1A2 (0.57) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL10925894 | 0.76 | TBXAS1 (0.38) | CYP11B1CYP11B2CYP19A1CYP1A2TBXAS1 | |
| SCHEMBL11310213 | 0.76 | IDO1 (0.52) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL9367910 | 0.76 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL10928334 | 0.75 | CYP19A1 (0.43) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL10927970 | 0.75 | ESR1 (0.43) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272545-A | FUNGICIDES, BACTERICIDE, ANTIPROTOZOA, SPERMATOCIDE | SYNTEX (U.S.A.) INC. (US) | 1981-06-09 | — | — | US | disclosed |