Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306094 | 0.71 | TSHR (0.54) | TSHRNR1H2NR1H3NR3C1CNR2 | |
| SCHEMBL11319605 | 0.71 | TSHR (0.44) | TSHRNR1H2NR1H3NR3C1CNR2 | |
| SCHEMBL5406221 | 0.64 | TSHR (0.66) | TSHRNR1H2NR1H3NR3C1CNR2 | |
| SCHEMBL3403622 | 0.63 | TSHR (0.59) | TSHRNR1H2NR1H3NR3C1CNR2 | |
| SCHEMBL28798683 | 0.63 | CTSS (0.42) | MAPK1 | |
| SCHEMBL28798686 | 0.63 | CTSS (0.42) | MAPK1 | |
| SCHEMBL11696683 | 0.63 | TSHR (0.64) | TSHRNR1H2NR1H3NR3C1CNR2 | |
| SCHEMBL11319163 | 0.63 | CNR2 (0.44) | TSHRNR3C1CNR2CYP2C19ALDH1A1 | |
| SCHEMBL179996 | 0.62 | TSHR (1.00) | TSHRNR1H2NR1H3CNR2CYP2C19 | |
| SCHEMBL7033156 | 0.62 | HSD11B1 (0.39) | NR1H2NR1H3CNR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268439-A | Basic azo dyestuffs having benzylammoniumamine substituent in the coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |