Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311493 | 0.89 | SLC6A3 (0.42) | SLC6A3SLC6A4MAPTNPC1RAB9A | |
| SCHEMBL11311539 | 0.80 | OPRM1 (0.53) | SLC6A3SLC6A4KMT2AMEN1SLC6A2 | |
| SCHEMBL31687570 | 0.80 | KMT2A (0.44) | SLC6A3SLC6A4MAPTNPC1RAB9A | |
| SCHEMBL11308078 | 0.80 | KMT2A (0.44) | SLC6A3SLC6A4MAPTNPC1RAB9A | |
| SCHEMBL14125442 | 0.78 | MAPT (0.39) | SLC6A3SLC6A4MAPTNPC1RAB9A | |
| SCHEMBL14125443 | 0.78 | MAPT (0.39) | SLC6A3SLC6A4MAPTNPC1RAB9A | |
| SCHEMBL10545643 | 0.75 | ALDH1A1 (0.45) | SLC6A3SLC6A4MAPTNPC1RAB9A | |
| SCHEMBL10543614 | 0.75 | ALDH1A1 (0.45) | SLC6A3SLC6A4MAPTNPC1RAB9A | |
| SCHEMBL10543020 | 0.75 | ALDH1A1 (0.45) | SLC6A3SLC6A4MAPTNPC1RAB9A | |
| SCHEMBL11303198 | 0.75 | MMP1 (0.42) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277490-A | Insecticidal 1-(2-naphthyl)-cyclobutane carboxylate | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1981-07-07 | — | — | US | disclosed |