Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038433 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL10713939 | 0.81 | L3MBTL1 (0.53) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL12856701 | 0.78 | PTPRC (0.56) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL21246924 | 0.76 | MAPT (0.66) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL19228099 | 0.74 | SMN1; SMN2 (0.48) | ALDH1A1MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL11175255 | 0.74 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL412227 | 0.74 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL16056409 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1NPSR1PTPRC | |
| SCHEMBL607022 | 0.73 | MAPT (0.67) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 | |
| SCHEMBL30958374 | 0.73 | MAPT (0.67) | ALDH1A1MAPTL3MBTL1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4301313-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS | ELI-LILLY AND COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4226887-A | P-BIPHENYLYLACETYLENE | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| US-3991212-A | PHENYLACETYLENE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
| US-3968251-A | Arylacetylene compounds as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |