Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 6/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 2/20 | 0.31 |
| ▸ | CCND1 | P24385 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744968 | 0.79 | GSK3B (0.46) | PPOXGSK3BPARP1AURKAAURKB | |
| SCHEMBL28709694 | 0.75 | GRIA1 (0.38) | PPOXGSK3BPARP1CHEK1CDK4 | |
| SCHEMBL2359305 | 0.71 | AURKA (0.34) | GSK3BPARP1AURKAAURKBCES1 | |
| SCHEMBL895684 | 0.65 | CES1 (0.56) | PPOXGSK3BMEN1MAPTKMT2A | |
| SCHEMBL1081008 | 0.64 | GSK3B (0.43) | PPOXGSK3BPARP1CDK4CCND1 | |
| SCHEMBL32089673 | 0.64 | GSK3B (0.43) | PPOXGSK3BPARP1CDK4CCND1 | |
| SCHEMBL2798146 | 0.64 | GSK3B (0.30) | GSK3B | |
| SCHEMBL1930015 | 0.62 | HTT (0.42) | AURKAAURKBMAPTKMT2AALDH1A1 | |
| SCHEMBL9016045 | 0.60 | KMT2A (0.34) | KMT2AALDH1A1TSHR | |
| SCHEMBL1045560 | 0.60 | L3MBTL1 (0.36) | KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248976-A | COMPRISING A PHOSPHORUS COMPOUND AND AN AROMATIC COMPOUND | CIBA-GEIGY AG (CH) | 1981-02-03 | — | — | US | disclosed |
| US-4172858-A | Flame-resistant polymer compositions | CIBA-GEIGY AG (CH) | 1979-10-30 | — | — | US | disclosed |
| US-4163731-A | HYDRAULIC FLUIDS | CIBA-GEIGY AG (CH) | 1979-08-07 | — | — | US | disclosed |